Secondary Extramedullary Plasmacytoma of the Duodenum: An Unusual Endoscopic Presentation

Antonietta Gerarda Gravina, Alessandro Federico, Antonello Sica, Francesco Paolo D'Armiento, Maria Giovanna Ferrara, Umberto Falcone, Marcello Dallio, Salvatore Guastafierro, Carmela Loguercio, Marco Romano


We describe an unusual case (a 79-year-old woman) of secondary extramedullary plasmacytoma (EMP) involving the duodenum. While all the previously reported cases of duodenal involvement by EMP (namely 20 cases) were characterized by the presence of ulcerative masses or ischemic necrotic lesions, in our case EMP led to the unusual finding of several non-polypoid lesions with a depressed central area. The final diagnosis was multiple myeloma IgA lambda, stage II A, with secondary duodenal EMP. To our knowledge this is the first report showing duodenal involvement by EMP with the aspect of multiple non-polypoid lesions.



Extramedullary plasmacytoma; Duodenum; Diagnosis

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Gastroenterology Research, bimonthly, ISSN 1918-2805 (print), 1918-2813 (online), published by Elmer Press Inc.                     
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