Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website http://www.gastrores.org

Case Report

Volume 11, Number 1, February 2018, pages 52-57

Autologous Graft-Versus-Host Disease of the Gastrointestinal Tract in Patients With Multiple Myeloma and Hematopoietic Stem Cell Transplantation

Figures

Figure 1.
Figure 1. Severe duodenal and colonic auto-GVHD present in case 1. (a, b) Duodenal biopsy showing focal mucosal sloughing, crypt injury and dropout, and epithelial apoptotic bodies (arrows) (inset in a: endoscopic appearance). (c, d) Colonic biopsy showing extensive mucosal sloughing, crypt injury and dropout, and epithelial apoptotic bodies (arrows) (inset in c: endoscopic appearance) (H&E stain. a, c: × 100; b, d: × 400).
Figure 2.
Figure 2. Biopsies after treatment for 13 days. (a, b) Colonic biopsy showing crypt regeneration and epithelial apoptotic bodies (arrows) (inset in a: endoscopic appearance). (c, d) Duodenal biopsy showing rare organisms of cryptosporidium (arrows) and highlighted by AFB (acid-fast) stain (d) (a: × 100; b, c: × 400; d: original, × 600).
Figure 3.
Figure 3. Mild colonic GVHD present in case 2. (a) Unremarkable endoscopic appearance of the colon. (b) Frequent apoptotic bodies present in the crypts of the colonic biopsy (arrows, H&E stain, × 400).