Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website http://www.gastrores.org

Original Article

Volume 5, Number 5, October 2012, pages 190-194

Hepatoprotective Property of Oral Silymarin is Comparable to N-Acetyl Cysteine in Acetaminophen Poisoning

Tables

Table 1. Levels of Serum Liver Enzymes in Studied Groups (Mean ± Standard Deviation)
 
ALT level (IU/L)AST level (IU/L)ALP level (IU/L)
*: as were tested by one-way ANOVA.
Group 128.82 ± 10.37153.36 ± 23.70163.18 ± 34.83
Group 293.89 ± 89.43194 ± 71.45266.67 ± 90.92
Group 326.18 ± 8.13102 ± 45.27247 ± 64.17
Group 431.89 ± 10.46157.44 ± 70.75255.33 ± 134.0
Group 540 ± 11.81169.27 ± 38.42256.82 ± 144.14
F5.044.421.85
Level of significant difference between groups*0.0020.0040.134

 

Table 2. Histopathologic Grading of Liver Necrosis in Studied Groups (Mean ± Standard Deviation)
 
Histopathologic grading
Group 23.44 ± 1.130
Group 31.30 ± 0.483
Group 41.38 ± 0.744
Group 53.67 ± 1.732