Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website http://www.gastrores.org

Original Article

Volume 5, Number 3, June 2012, pages 97-102


Effect of Acute Surgical Stress on Serum Ghrelin Levels

Figure

Figure 1.
Figure 1. Fluctuations in the ghrelin levels during the different time points of the study. F = 0.954, P = 0.339.

Tables

Table 1. Patients Demographic Data and Ghrelin Levels at Each Time Point
 
Type of SurgeryCholocystectomy (n = 10)Colectomy (n = 15)P value
Ghrelin 1: preoperatively; Ghrelin 2: After intubation; Ghrelin 3: 1 hr postoperatively; Ghrelin 4: 5 hr postoperatively; Ghrelin 5: 24 hr postoperatively; Ghrelin 6: 48 hr postoperatively; BMI: Body Mass Index.
Age (mean ± SD)46.8 ± 15.7656.86 ± 14.32NS
BMI (mean ± SD)27.6 ± 4.4227.38 ± 4.55NS
Gender (M/F)3/79/6NS
Ghrelin 1 (ng/mL, mean ± SD)5.0 ± 1.54.8 ± 0.6NS
Ghrelin 2 (ng/mL, mean ± SD)5.1 ± 1.54.8 ± 0.6NS
Ghrelin 3 (ng/mL, mean ± SD)5.3 ± 1.34.9 ± 0.5NS
Ghrelin 4 (ng/mL, mean ± SD)8.2 ± 2.87.4 ± 1.4NS
Ghrelin 5 (ng/mL, mean ± SD)8.4 ± 3.47.4 ± 1.8NS
Ghrelin 6 (ng/mL, mean ± SD)5.3 ± 1.35.0 ± 0.6NS

 

Table 2. Comparison of Ghrelin Levels Between Each Time Point in Group
 
Time Point(ng/mL, mean ± SD)123456
T 1: A preoperatively, T 2: After intubation, T 3: 1 hr postoperatively, T 4: 5 hr postoperatively, T 5: 24 hr postoperatively, T 6: 48 hr postoperatively.
15.0 ± 1.5N.SN.SN.S0.0010.008N.S
25.1 ± 1.5----N.SN.S0.0010.010N.S
35.3 ± 1.3--------N.S0.0030.019N.S
48.2 ± 2.8------------N.SN.S0.005
58.4 ± 3.4----------------N.S0.026
65.3 ± 1.3-------------------N.S

 

Table 3. Comparison of Ghrelin Levels Between Each Time Point in Group B
 
Time Point(ng/mL, mean ± SD)123456
T 1: preoperatively, T 2: After intubation, T 3: 1 hr postoperatively, T 4: 5 hr postoperatively, T 5: 24 hr postoperatively, T 6: 48 hr postoperatively.
14.8 ± 0.6N.SN.SN.S0.0010.001N.S
24.8 ± 0.6----N.SN.S0.0000.000N.S
34.9 ± 0.5--------N.S0.0000.001N.S
47.4 ± 1.4------------N.SN.S0.000
57.4 ± 1.8----------------N.S0.001
65.0 ± 0.6-------------------N.S