Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access |
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc |
Journal website http://www.gastrores.org |
Original Article
Volume 5, Number 3, June 2012, pages 97-102
Effect of Acute Surgical Stress on Serum Ghrelin Levels
Figure
Tables
Type of Surgery | Cholocystectomy (n = 10) | Colectomy (n = 15) | P value |
---|---|---|---|
Ghrelin 1: preoperatively; Ghrelin 2: After intubation; Ghrelin 3: 1 hr postoperatively; Ghrelin 4: 5 hr postoperatively; Ghrelin 5: 24 hr postoperatively; Ghrelin 6: 48 hr postoperatively; BMI: Body Mass Index. | |||
Age (mean ± SD) | 46.8 ± 15.76 | 56.86 ± 14.32 | NS |
BMI (mean ± SD) | 27.6 ± 4.42 | 27.38 ± 4.55 | NS |
Gender (M/F) | 3/7 | 9/6 | NS |
Ghrelin 1 (ng/mL, mean ± SD) | 5.0 ± 1.5 | 4.8 ± 0.6 | NS |
Ghrelin 2 (ng/mL, mean ± SD) | 5.1 ± 1.5 | 4.8 ± 0.6 | NS |
Ghrelin 3 (ng/mL, mean ± SD) | 5.3 ± 1.3 | 4.9 ± 0.5 | NS |
Ghrelin 4 (ng/mL, mean ± SD) | 8.2 ± 2.8 | 7.4 ± 1.4 | NS |
Ghrelin 5 (ng/mL, mean ± SD) | 8.4 ± 3.4 | 7.4 ± 1.8 | NS |
Ghrelin 6 (ng/mL, mean ± SD) | 5.3 ± 1.3 | 5.0 ± 0.6 | NS |
Time Point | (ng/mL, mean ± SD) | 1 | 2 | 3 | 4 | 5 | 6 |
---|---|---|---|---|---|---|---|
T 1: A preoperatively, T 2: After intubation, T 3: 1 hr postoperatively, T 4: 5 hr postoperatively, T 5: 24 hr postoperatively, T 6: 48 hr postoperatively. | |||||||
1 | 5.0 ± 1.5 | N.S | N.S | N.S | 0.001 | 0.008 | N.S |
2 | 5.1 ± 1.5 | ---- | N.S | N.S | 0.001 | 0.010 | N.S |
3 | 5.3 ± 1.3 | ---- | ---- | N.S | 0.003 | 0.019 | N.S |
4 | 8.2 ± 2.8 | ---- | ---- | ---- | N.S | N.S | 0.005 |
5 | 8.4 ± 3.4 | ---- | ---- | ---- | ---- | N.S | 0.026 |
6 | 5.3 ± 1.3 | ---- | ---- | ---- | ---- | --- | N.S |
Time Point | (ng/mL, mean ± SD) | 1 | 2 | 3 | 4 | 5 | 6 |
---|---|---|---|---|---|---|---|
T 1: preoperatively, T 2: After intubation, T 3: 1 hr postoperatively, T 4: 5 hr postoperatively, T 5: 24 hr postoperatively, T 6: 48 hr postoperatively. | |||||||
1 | 4.8 ± 0.6 | N.S | N.S | N.S | 0.001 | 0.001 | N.S |
2 | 4.8 ± 0.6 | ---- | N.S | N.S | 0.000 | 0.000 | N.S |
3 | 4.9 ± 0.5 | ---- | ---- | N.S | 0.000 | 0.001 | N.S |
4 | 7.4 ± 1.4 | ---- | ---- | ---- | N.S | N.S | 0.000 |
5 | 7.4 ± 1.8 | ---- | ---- | ---- | ---- | N.S | 0.001 |
6 | 5.0 ± 0.6 | ---- | ---- | ---- | ---- | --- | N.S |