Gastroenterol Res

Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access

Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc

Journal website http://www.gastrores.org

Original Article

Volume 1, Number 1, December 2008, pages 49-54

Dynamic Changes of Soluble Fas and IL-2/IL-10 in serum and Fas Expression in Lung in the Rats of Acute Necrotizing Pancreatitis

Figure

Figure 1. Histological changes in pulmonary tissue after induction of ANP. A: Lung tissue in the P group at 0.5 hour (HE, original magnification ×100); B: Lung tissue in the P group at 12 hour (HE, original magnification ×100); C: Fas had a lower expression in pulmonary tissue in the P group at 0.5 hour (original magnification ×400); D: Fas had a higher expression in pulmonary tissue in the P group at 12 hour (original magnification ×400).

Tables

**Table 1.** Serum IL-2 level (pg/ml) in each group
Group	0.5 hour	2 hour	6 hour	12 hour
^*P < 0.01 vs. C group. C: control group; P: acute necrotic pancreatitis group.
C	2.79 ± 0.51	2.93 ± 0.89	4.81 ± 1.23	3.41 ± 0.72
P	3.53 ± 0.62^*	4.35 ± 1.11^*	6.94 ± 1.55^*	4.80 ± 1.10^*

**Table 2.** Serum IL-10 level (pg/ml) in each group
Group	0.5 hour	2 hour	6 hour	12 hour
^*P < 0.01 vs. C group. C: control group; P: acute necrotic pancreatitis group.
C	54.61 ± 15.81	141.15 ± 40.21	89.18 ± 32.52	77.15 ± 22.60
P	47.34 ± 14.62	156.12 ± 43.10	494.98 ± 11.23^*	93.28 ± 25.81^*

**Table 3.** Serum IL-2/IL-10 ratio in each group
Group	0.5 hour	2 hour	6 hour	12 hour
^*P <0.01 vs. C group. C: control group; P: acute necrotic pancreatitis group.
C	0.05 ± 0.01	0.02 ± 0.01	0.05 ± 0.02	0.04 ± 0.01
P	0.07 ± 0.02^*	0.03 ± 0.01^*	0.01 ± 0.01^*	0.05 ± 0.02

**Table 4.** Fas/APO-1 level (pg/ml) in each group
Group	0.5 hour	2 hour	6 hour	12 hour
C: control group; P: acute necrotic pancreatitis group.
C	3.16 ± 0.75	4.05 ± 1.08	5.93 ± 1.52	4.62 ± 1.23
P	3.31 ± 0.80	4.32 ± 1.11	5.41 ± 1.47	4.44 ± 1.16

**Table 5.** Pulmonary tissues injury in each group
Group	0.5 hour				2 hour				6 hour				12 hour
	0	I	II	III	0	I	II	III	0	I	II	III	0	I	II	III
^*P<0.01 vs. C group. C: control group; P: acute necrotic pancreatitis group.
C	8	0	0	0	7	1	0	0	7	1	0	0	7	1	0	0
P	2	5	1	0^*	1	5	2	0^*	0	4	3	1^*	0	3	4	1^*