Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website https://www.gastrores.org

Original Article

Volume 000, Number 000, July 2024, pages 000-000


Pre-Cut Papillotomy Versus Endoscopic Ultrasound-Rendezvous for Difficult Biliary Cannulation: A Systematic Review and Meta-Analysis

Figures

Figure 1.
Figure 1. The PRISMA flow chart illustrating how the final studies were selected. PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses.
Figure 2.
Figure 2. Forrest plot results of meta-analysis. (a) Forrest plot comparing technical success rate of pre-cut papillotomy and EUS-rendezvous. (b) Forrest plot comparing post-procedure pancreatitis rate between pre-cut papillotomy and EUS-rendezvous. (c) Forrest plot comparing bleeding rate between pre-cut papillotomy and EUS-rendezvous. (d) Forrest plot comparing overall complications rate between pre-cut papillotomy and EUS-rendezvous.

Tables

Table 1. Baseline Study Characteristics and Demographics
 
Dhir et al, 2011 [19]Dalal et al, 2022 [20]Choudhury et al, 2022 [21]Tang et al, 2023 [22]
ERCP: endoscopic retrograde cholangiopancreatography; EUS: endoscopic ultrasound.
Study periodMay 2010 to April 20113-year study periodJuly 2020 to May 2021January 2014 to October 2022
Single/multicenterSingle centerSingle centerSingle centerSingle center
Mean age, years48.551.575.5
Total ERCP (n)4,3624711008,626
Males, n (%)124 (61%)330 (70.1%)245 (56%)
Pre-cut papillotomy (n)14423050375
EUS-rendezvous (n)58355062

 

Table 2. ERCP Indications
 
Dhir et al, 2011 [19]Dalal et al, 2022 [20]Choudhury et al, 2022 [21]Tang et al, 2023 [22]
EUS: endoscopic ultrasound; ERCP: endoscopic retrograde cholangiopancreatography; CBD: common bile duct.
IndicationsPre-cutEUSPre-cutEUS
Ampullary cancer9450Benign biliary disease81
Malignant biliary strictures1103910
Benign biliary stricture1071093
CBD stone15821420747
Cholangiocarcinoma373
Pancreatic cancer82605
Malignant obstruction due to lymph node metastasis from other cancers443
Gallbladder cancer60

 

Table 3. Outcomes for Individual Studies
 
Dhir et al, 2011 [19]Dalal et al, 2022 [20]Choudhury et al, 2022 [21]Tang et al, 2023 [22]
EUS: endoscopic ultrasound; N/A: not available.
Technical success (n)
  Pre-cut papillotomy13822045293
  EUS-rendezvous57344657
Pancreatitis (n)
  Pre-cut papillotomy420532
  EUS-rendezvous0052
Bleeding (n)
  Pre-cut papillotomy69N/A12
  EUS-rendezvous00N/A1
Overall complications (n)
  Pre-cut papillotomy1032556
  EUS-rendezvous22056