Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website https://www.gastrores.org

Original Article

Volume 17, Number 4, August 2024, pages 175-182

Clinical Efficacy of Transcatheter Arterial Chemoembolization Combined With Percutaneous Microwave Coagulation Therapy for Advanced Hepatocellular Carcinoma

Tables

Table 1. Clinical Characteristics
 
Control group (n = 26)Experiment group (n = 57)P value
AFP: alpha-fetoprotein; WHO: the World Health Organization; HAPS: hepatic arterio-portal shunts.
Gender (male/female)1.0
  Male2249
  Female48
Tumor diameter0.834
  < 5 cm616
  ≥ 5 cm2041
AFP level0.371
  ≤ 20 ng/mL24
  20 - 400 ng/mL417
  ≥ 400 ng/mL2036
Child-Pugh score0.401
  A620
  B2037
Clinical stages0.990
  Phase IIa24
  Phase IIb2146
  Phase IIIa37
WHO classification0.857
  Grade I1227
  Grade II821
  Grade III35
  Grade VI34
Portal vein tumor thrombus8220.658
Merge HAPS491.0

 

Table 2. Analysis of Clinical Efficacy
 
Control group (n = 26)Experiment group (n = 57)
Response
  Complete response311
  Partial response717
  Stable disease819
  Progressive disease810
Objective response rate38.4%49.1%
Disease control rate69.2%82.4%

 

Table 3. Quantitative Analysis of AFP After Treatment
 
Control group (n = 26)Experiment group (n = 57)P value
AFP: alpha-fetoprotein.
AFP level0.045
≤ 20 ng/mL419
20 - 400 ng/mL721
≥ 400 ng/mL1517

 

Table 4. Analysis of Survival Time
 
Control group (n = 26), n (%)Experiment group (n = 57), n (%)P value
0.5 years18 (69.2%)46 (80.7%)0.271
1 year16 (61.3%)43 (75.4%)0.205
1.5 years13 (50.0%)38 (66.7%)0.224
2 years8 (30.8%)30 (52.6%)0.096

 

Table 5. Analysis of Cumulative Recurrence and Metastasis Rates
 
Control group (n = 26), n (%)Experiment group (n = 57), n (%)P value
0.5 years4 (15.4%)5 (8.8%)0.451
1 year9 (34.6%)12 (21.1%)0.276
1.5 years13 (50.0%)17 (29.8%)0.08
2 years18 (69.2%)21 (36.8%)0.008

 

Table 6. The Occurrence of Complications
 
Control group (n = 26), n (%)Experiment group (n = 57), n (%)P value
Fever14 (53.8%)29 (50.9%)0.760
Pain9 (34.6%)23 (40.3%)0.054
Nausea and vomiting17 (65.4%)40 (70.2%)0.068
Elevated transaminase11 (42.3%)24 (42.1%)0.931
Jaundice5 (19.2%)13 (22.8%)0.427