Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website https://www.gastrores.org

Case Report

Volume 16, Number 1, February 2023, pages 50-55

Ischemic Reperfusion Injury After Liver Transplantation: Is There a Place for Conservative Management?

Figures

Figure 1.
Figure 1. The trend of ALT in the cases. ALT: alanine aminotransferase.
Figure 2.
Figure 2. Liver during reperfusion phase of liver transplantation. Blue spots on liver surface indicate areas with impaired perfusion.

Tables

Table 1. Comparison Between the Course, Management, and Outcomes of Three Cases of IRI After Liver Transplantation
 
VariablesCase 1Case 2Case 3
AIH: autoimmune hepatitis; AST: aspartate aminotransferase; ALT: alanine aminotransferase; INR: international normalized ratio.
Age (years)325743
Cirrhosis etiologyAIH type 1Alcoholic cirrhosisCryptogenic
The peak of liver injury post-transplant (h)244824
Peak AST (U/L)13,16010,16020,248
Peak ALT (U/L)7,5809,6694,570
Peak total bilirubin (mg/dL)13.78.710.3
Peak INR3.373.23.7
ManagementSupportive with a trial of steroids for 3 daysSupportive treatmentSupportive treatment
Follow-up 5 years laterNo complicationsNo complicationsNo complications

 

Table 2. The Course of AST and ALT for 21 Days After Liver Transplantation
 
Postoperative dayCase 1Case 2Case 3
AST (U/L)ALT (U/L)AST (U/L)ALT (U/L)AST (U/L)ALT (U/L)
AST: aspartate aminotransferase; ALT: alanine aminotransferase.
01,3096633,3652,80817,7784,113
113,1607,5803,9783,41320,2484,570
24,6022,58410,1606,9967,1662,236
79061713985886
21271542473923