| Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc |
| Journal website https://www.gastrores.org |
Review
Volume 15, Number 6, December 2022, pages 285-296
Radiation in Gastroenterology
Tables
| CTCAE version 5.0 | |
|---|---|
| CTCAE: Common Terminology Criteria for Adverse Events. | |
| Grade 1 | Asymptomatic |
| Grade 2 | Symptomatic; altered swallowing/eating; oral supplements indicated |
| Grade 3 | Severely altered swallowing/eating; tube feeding, total parenteral nutrition, or hospitalization indicated |
| Grade 4 | Life-threatening consequences; urgent operative intervention indicated |
| Grade 5 | Death |
| RTOG scale | |
|---|---|
| RTOG: Radiation Therapy Oncology Group. | |
| Grade 1 | Mild dysphagia or odynophagia, requires soft diet, topical anesthetic or non-narcotic agents |
| Grade 2 | Moderate dysphagia or odynophagia, requiring liquid diet or narcotic agents |
| Grade 3 | Severe dysphagia or odynophagia with dehydration or weight loss (> 15% or pretreatment baseline), requiring nasogastric feeding |
| Grade 4 | Complete stricture, ulceration, perforation or fistula |
| Grade 5 | Death |
| Organ | Radiation dose threshold (Gy) | Period of time to develop effect |
|---|---|---|
| Gastrointestinal mucosal lining loss | 6 | 6 to 9 days |
| Reduced production of bone marrow hematopoietic cells | 0.5 | 1 to 2 months |
| Ovaries - permanent sterility | 2.5 to 6 | < 1 week |
| Testes - temporary sterility | 0.15 | 3 to 9 weeks |
| Permanent sterility | 3.5 to 6 | 3 weeks |
| Skin - erythema | 3 to 6 | 1 to 4 weeks |
| Temporary hair loss (depilation) | 4 | 2 to 3 weeks |
| Death and scarring (necrosis) | 5 to 10 | 1 to 4 weeks |