Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
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Case Report

Volume 13, Number 4, August 2020, pages 150-154


Severe Sprue-Like Enteropathy and Colitis due to Olmesartan: Lessons Learned From a Rare Entity

Figures

Figure 1.
Figure 1. (a) Sigmoid colon mucosa (hematoxylin and eosin, × 400) showing chronic inflammation in the superficial portion of the lamina propria and mild intraepithelial lymphocytosis with surface epithelial injury (lymphocytic colitis-like injury) with rare acute inflammatory cells in the lamina propria and surface epithelium (arrow). (b) Sigmoid colon mucosa (hematoxylin and eosin, × 100) showing chronic inflammation in the superficial portion of the lamina propria and mild intraepithelial lymphocytosis with surface epithelial injury (lymphocytic colitis-like injury) with rare acute inflammatory cells in the lamina propria (stars) and surface epithelium (arrow).
Figure 2.
Figure 2. (a) Duodenal mucosa (hematoxylin and eosin, × 100) with subtotal villous blunting (arrows) with chronic duodenitis with an increase in chronic inflammation of the lamina propria consisting of a mixed population of lymphocytes, plasma cells, and eosinophils as well as an increase in intraepithelial lymphocytes (intraepithelial lymphocytosis). (b) Duodenal mucosa (hematoxylin and eosin, × 200) with subtotal villous blunting with chronic duodenitis with an increase in chronic inflammation of the lamina propria consisting of a mixed population of lymphocytes, plasma cells, and eosinophils as well as an increase in intraepithelial lymphocytes (intraepithelial lymphocytosis; arrows).