Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access
Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc
Journal website http://www.gastrores.org

Case Report

Volume 12, Number 5, October 2019, pages 263-266

Acute Liver Injury in a Patient Treated With Rosuvastatin: A Rare Adverse Effect

Figures

Figure 1.
Figure 1. Abdominal ultrasound. The liver is mildly heterogeneous with coarsened echotexture, non-specific findings that can be seen in hepatitis.
Figure 2.
Figure 2. Histopathologic images of the patient’s DILI from liver biopsy showing acute severe hepatitis. There is a portal and lobular mixed inflammatory infiltrate comprised of neutrophils, lymphocytes, plasma cells and scattered eosinophils. There is interface activity present and bile duct damage. The histopathology is consistent with an immune-mediated drug reaction vs. less likely an infectious etiology. (a) H&E stain (× 200). (b) H&E stain (× 400). DILI: drug-induced liver injury.
Figure 3.
Figure 3. Abdominal CT scan. There is hypoattenuation around the portal area consistent with mild periportal edema. CT: computed tomography.