| Gastroenterology Research, ISSN 1918-2805 print, 1918-2813 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, Gastroenterol Res and Elmer Press Inc |
| Journal website http://www.gastrores.org |
Original Article
Volume 11, Number 5, October 2018, pages 355-360
Clinical, Histologic, and Immunophenotypic Features of Serrated Polyps in Patients With Inflammatory Bowel Disease
Tables
| Feature | HP | SSA/P | P value |
|---|---|---|---|
| Pts: patients; y: years. | |||
| Number of cases (number of patients) | 25 (17 pts) | 11 (11 pts) | |
| Age (y), mean (range) | 47.8 (29 to 75) | 55.2 (29 to 68) | 0.2 |
| Male/female | 7/10 | 6/5 | 0.7 |
| IBD type (UC vs. CD) | 14:11 | 8:3 | 0.25 |
| Mean IBD duration at index, years (IQR) | 17.7 (1 to 40) | 12.7 (3 to 20) | 0.42 |
| Polyp/flat lesion | 22/3 | 10/1 | 1 |
| Right/left colon | 9/11 | 7/4 | 0.46 |
| Study group | Control group | |||
|---|---|---|---|---|
| SSA/P | HP | SSA/P | HP | |
| *Two cases of SSA/P in study group and one HP from the control group were excluded from BRAF evaluation with inadequate tissue for interpretation after BRAF immunostain. | ||||
| Site | ||||
| Left (%) | 4 (36.4%) | 15 (60.0%) | 4 (26.7%) | 15 (60.0%) |
| Right (%) | 7 (63.6%) | 10 (40.0%) | 11 (73.3%) | 10 (40.0%) |
| P value | 0.68 | 1 | ||
| BRAF* | ||||
| Positive (%) | 5 (55.6%) | 13 (52.0%) | 11 (73.3%) | 13 (54.2%) |
| Negative (%) | 4 (44.4%) | 12 (48.0%) | 4 (26.7%) | 11 (45.8%) |
| P value | 0.41 | 1 | ||
| β-catenin | ||||
| Positive (%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Negative (%) | 11 (100.0%) | 25 (100.0%) | 15 (100.0%) | 25 (100.0%) |
| P value | 1 | 1 | ||